SAMe

Medical abbreviation · Drug

SAMe
Stands forS-adenosylmethionine
CategoriesMedical

SAMe stands for S-adenosylmethionine, a drug abbreviation.

Naturally occurring compound involved in methylation reactions, sold in the US as a dietary supplement for depression, osteoarthritis and liver health. In parts of Europe it is a prescription medication.

Example: Patient started SAMe 400 mg BID for mood; discussed interaction with sertraline.

Usage notes

Pronounced "sammy". SAMe became available as a US supplement in 1999. Some studies suggest modest antidepressant effects, but evidence quality is limited. Combining it with serotonergic antidepressants may raise the risk of serotonin syndrome, and it can trigger mania in bipolar disorder. Products vary in stability and actual content.

More drug abbreviations

  • RhIG – Rho(D) immune globulin
  • RIF – Rifampin
  • RIG – Rabies immune globulin
  • RIPE – Rifampin, isoniazid, pyrazinamide and ethambutol
  • RPV – Rilpivirine
  • RTV – Ritonavir
  • SCIG – Subcutaneous immunoglobulin
  • SNP – Sodium nitroprusside
  • SOF – Sofosbuvir
  • SPS – Sodium polystyrene sulfonate
  • SSKI – Saturated solution of potassium iodide
  • SSZ – Sulfasalazine

See all 170 drug abbreviations →

Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.