PGx

Medical abbreviation · Pharmacology

PGx
Stands forPharmacogenomics
CategoriesMedical

PGx stands for Pharmacogenomics, a pharmacology abbreviation.

Study and clinical use of genetic variations that affect how individuals respond to drugs, such as variants in CYP2C19, CYP2D6, TPMT or HLA genes. Test results can guide drug choice and dose.

Example: PGx panel: CYP2C19 poor metabolizer; switch clopidogrel to ticagrelor.

Usage notes

The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes gene-drug guidelines. Screening for HLA-B*15:02 before carbamazepine is recommended for patients of Asian ancestry because of the risk of Stevens-Johnson syndrome, and the FDA added a boxed warning to clopidogrel about CYP2C19 poor metabolizers in 2010.

More pharmacology abbreviations

  • MTD – Maximum tolerated dose
  • NTI – Narrow therapeutic index
  • OIC – Opioid-induced constipation
  • OIH – Opioid-induced hyperalgesia
  • P-gp – P-glycoprotein
  • PD – Pharmacodynamics
  • PIM – Potentially inappropriate medication
  • PK – Pharmacokinetics
  • SAE – Serious adverse event
  • STOPP – Screening Tool of Older Persons' Prescriptions
  • t1/2 – Half-life
  • TI – Therapeutic index

See all 36 pharmacology abbreviations →

Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.