PAMORA
Medical abbreviation · Drug Class
| Stands for | Peripherally acting mu-opioid receptor antagonist |
|---|---|
| Categories | Medical |
PAMORA stands for Peripherally acting mu-opioid receptor antagonist, a drug class abbreviation.
Drugs that block opioid receptors in the gut but do not cross into the brain, relieving opioid-induced constipation without reversing pain relief. Methylnaltrexone, naloxegol and naldemedine are approved for this use.
Example: OIC despite senna and PEG: PAMORA methylnaltrexone 12 mg subcut every other day.
Usage notes
Alvimopan, another PAMORA, is used in hospitals to speed bowel recovery after surgery and is restricted under a REMS program because of heart attack signals with long-term use. PAMORAs are contraindicated in known or suspected bowel obstruction. Pronounced "pa-MOR-a".
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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.