NSCLC
Medical abbreviation · Hematology and Oncology
| Stands for | Non-small cell lung cancer |
|---|---|
| Categories | Medical |
NSCLC stands for Non-small cell lung cancer, a hematology and oncology abbreviation.
Group of lung cancers, mainly adenocarcinoma and squamous cell carcinoma, accounting for about 85 percent of lung cancers. Lung cancer is the leading cause of cancer death in the United States and worldwide.
Example: Stage IV NSCLC, adenocarcinoma, EGFR exon 19 deletion: first-line osimertinib.
Usage notes
Every advanced nonsquamous NSCLC should undergo broad molecular testing for targetable alterations such as EGFR, ALK, ROS1, KRAS G12C, BRAF, MET, RET, HER2 and NTRK, plus PD-L1 staining, before treatment. The US Preventive Services Task Force recommends annual low-dose CT screening for adults aged 50 to 80 with at least a 20 pack-year history who smoke or quit within 15 years. Adenocarcinoma is the most common type in never-smokers.
Related abbreviations
More hematology and oncology abbreviations
- NCCN – National Comprehensive Cancer Network
- NCI – National Cancer Institute
- NED – No evidence of disease
- NET – Neuroendocrine tumor
- NGS – Next-generation sequencing
- NHL – Non-Hodgkin lymphoma
- ORR – Objective response rate
- OS – Overall survival
- PCI – Prophylactic cranial irradiation
- pCR – Pathologic complete response
- PD – Progressive disease
- PD-1 – Programmed cell death protein 1
See all 144 hematology and oncology abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.