GIP/GLP-1 RA
Medical abbreviation · Drug Class
| Stands for | Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist |
|---|---|
| Categories | Medical |
GIP/GLP-1 RA stands for Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, a drug class abbreviation.
Dual incretin agonist class whose first member, tirzepatide, is injected once weekly as Mounjaro for type 2 diabetes and Zepbound for obesity and obstructive sleep apnea. It activates two gut hormone receptors.
Example: Start GIP/GLP-1 RA tirzepatide 2.5 mg weekly x 4 weeks, then 5 mg.
Usage notes
Tirzepatide was approved for type 2 diabetes in 2022 and for chronic weight management in 2023. In the SURMOUNT-1 trial, the highest dose produced about 21 percent average weight loss at 72 weeks, more than seen with semaglutide in its trials. Side effects and the thyroid C-cell tumor boxed warning are similar to GLP-1 receptor agonists.
Related abbreviations
More drug class abbreviations
- ERA – Endothelin receptor antagonist
- ERT – Enzyme replacement therapy
- ESA – Erythropoiesis-stimulating agent
- FGA – First-generation antipsychotic
- FQ – Fluoroquinolone
- GC – Glucocorticoid
- GLP-1 RA – Glucagon-like peptide-1 receptor agonist
- GnRHa – Gonadotropin-releasing hormone agonist
- GPI – Glycoprotein IIb/IIIa inhibitor
- H2RA – Histamine-2 receptor antagonist
- HRT – Hormone replacement therapy
- ICI – Immune checkpoint inhibitor
See all 113 drug class abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.