GLP-1 RA

Medical abbreviation · Drug Class

GLP-1 RA
Stands forGlucagon-like peptide-1 receptor agonist
CategoriesMedical

GLP-1 RA stands for Glucagon-like peptide-1 receptor agonist, a drug class abbreviation.

Drugs such as semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide and dulaglutide that mimic a gut hormone to boost insulin release, slow stomach emptying and reduce appetite. They treat type 2 diabetes and obesity and lower cardiovascular risk.

Example: Titrate GLP-1 RA: semaglutide 0.25 mg weekly x 4 weeks, then 0.5 mg.

Usage notes

Exenatide, the first (2005), was derived from a protein in Gila monster saliva. Semaglutide 2.4 mg produced about 15 percent average weight loss in the STEP-1 trial, and demand caused nationwide shortages from 2022. A boxed warning about thyroid C-cell tumors in rodents rules them out for people with a family history of medullary thyroid cancer or MEN2.

More drug class abbreviations

  • ERT – Enzyme replacement therapy
  • ESA – Erythropoiesis-stimulating agent
  • FGA – First-generation antipsychotic
  • FQ – Fluoroquinolone
  • GC – Glucocorticoid
  • GIP/GLP-1 RA – Glucose-dependent insulinotropic polypeptide and glucagon-like…
  • GnRHa – Gonadotropin-releasing hormone agonist
  • GPI – Glycoprotein IIb/IIIa inhibitor
  • H2RA – Histamine-2 receptor antagonist
  • HRT – Hormone replacement therapy
  • ICI – Immune checkpoint inhibitor
  • ICS – Inhaled corticosteroid

See all 113 drug class abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.