TMA
Medical abbreviation · Hematology and Oncology
| Stands for | Thrombotic microangiopathy |
|---|---|
| Categories | Medical |
TMA stands for Thrombotic microangiopathy, a hematology and oncology abbreviation.
Umbrella term for disorders in which small blood vessels are damaged and blocked by clots, producing microangiopathic hemolytic anemia, low platelets and organ injury, especially to the kidneys and brain. It includes TTP, hemolytic uremic syndrome and many secondary forms.
Example: Post-transplant TMA with rising creatinine, schistocytes and hypertension; tacrolimus level checked.
Usage notes
Secondary causes include drugs (calcineurin inhibitors, gemcitabine, quinine), malignant hypertension, pregnancy complications such as HELLP, autoimmune disease and stem cell transplantation. Complement-mediated (atypical) HUS is treated with complement inhibitors such as eculizumab. Kidney biopsy shows characteristic vessel changes when the diagnosis is unclear.
Related abbreviations
More hematology and oncology abbreviations
- SCT – Sickle cell trait
- SD – Stable disease
- SEER – Surveillance, Epidemiology, and End Results Program
- TACO – Transfusion-associated circulatory overload
- TKI – Tyrosine kinase inhibitor
- TLS – Tumor lysis syndrome
- TMB – Tumor mutational burden
- TNBC – Triple-negative breast cancer
- TNM – Tumor, Node, Metastasis
- TRALI – Transfusion-related acute lung injury
- TTP – Thrombotic thrombocytopenic purpura
- VRd – Velcade (bortezomib), Revlimid (lenalidomide), dexamethasone
See all 144 hematology and oncology abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.