TLS
Abbreviation with 2 meanings
| Stands for | Transport Layer Security |
|---|---|
| Meanings | 2 |
| Categories | Technology & Computing, Medical |
TLS has two meanings. It stands for Transport Layer Security (cybersecurity) or Tumor lysis syndrome (hematology and oncology).
Meanings of TLS at a glance
| # | TLS stands for | Context |
|---|---|---|
| 1 | Transport Layer Security | Technology & Computing › Cybersecurity |
| 2 | Tumor lysis syndrome | Medical › Hematology and Oncology |
1. Transport Layer Security
Technology & Computing · Cybersecurity Abbreviations
The cryptographic protocol that encrypts and authenticates data sent over networks, protecting HTTPS websites, email, VPNs and APIs. During a handshake, the client checks the server's certificate and both sides agree on session keys.
Example: The load balancer terminates TLS and forwards plain HTTP to the app servers on the private network.
The IETF released TLS 1.0 in 1999 as the successor to SSL 3.0, followed by 1.1 (2006), 1.2 (2008) and 1.3 (2018). Version 1.3 removed outdated ciphers, made forward secrecy mandatory and cut the handshake to one round trip. TLS 1.0 and 1.1 were formally deprecated in 2021 and are rejected by major browsers. Many people still say SSL when they mean TLS.
2. Tumor lysis syndrome
Medical · Hematology and Oncology Abbreviations
Metabolic emergency caused by rapid breakdown of cancer cells, typically after starting treatment for fast-growing cancers, releasing potassium, phosphate and uric acid into the blood. It can cause kidney failure, dangerous heart rhythms and seizures.
Example: Day 1 of chemo for Burkitt lymphoma: K 6.4, phosphate 8.2, uric acid 14: TLS, rasburicase and nephrology consult.
The Cairo-Bishop criteria (2004) define laboratory and clinical TLS. High-risk settings include Burkitt lymphoma, acute leukemias with high white counts, bulky lymphoma and starting venetoclax in CLL. Prevention relies on aggressive hydration and uric acid control with allopurinol or rasburicase; rasburicase is contraindicated in G6PD deficiency because it can cause severe hemolysis.
Related abbreviations
More cybersecurity abbreviations
- SQLi – SQL injection
- SSL – Secure Sockets Layer
- SSO – Single sign-on
- SSRF – Server-side request forgery
- Tor – The Onion Router
- TOTP – Time-based one-time password
- TPM – Trusted Platform Module
- TTP – Tactics, techniques and procedures
See all 119 cybersecurity abbreviations →
More hematology and oncology abbreviations
- SD – Stable disease
- SEER – Surveillance, Epidemiology, and End Results Program
- TACO – Transfusion-associated circulatory overload
- TKI – Tyrosine kinase inhibitor
- TMA – Thrombotic microangiopathy
- TMB – Tumor mutational burden
- TNBC – Triple-negative breast cancer
- TNM – Tumor, Node, Metastasis
See all 144 hematology and oncology abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.