PTLD
Medical abbreviation · Hematology and Oncology
| Stands for | Post-transplant lymphoproliferative disorder |
|---|---|
| Categories | Medical |
PTLD stands for Post-transplant lymphoproliferative disorder, a hematology and oncology abbreviation.
Spectrum of lymphoid growths, from benign proliferations to aggressive lymphoma, that develop after solid organ or stem cell transplantation because of immunosuppression. Most are driven by Epstein-Barr virus.
Example: Kidney transplant recipient with rising EBV load and new abdominal mass: PTLD, tacrolimus reduced, rituximab started.
Usage notes
Risk is highest in the first year after transplant and in EBV-negative recipients of EBV-positive organs, which is common in children. First steps include reducing immunosuppression and giving rituximab, with chemotherapy for aggressive forms. EBV-specific T-cell therapy (tabelecleucel) was approved in Europe in 2022 for relapsed EBV-positive PTLD.
Related abbreviations
More hematology and oncology abbreviations
- Ph – Philadelphia chromosome
- PMF – Primary myelofibrosis
- PNH – Paroxysmal nocturnal hemoglobinuria
- PR – Partial response
- PRBC – Packed red blood cells
- PS – Performance status
- PV – Polycythemia vera
- R-CHOP – Rituximab, cyclophosphamide, hydroxydaunorubicin (doxorubicin)…
- RECIST – Response Evaluation Criteria in Solid Tumors
- RT – Radiation therapy
- SBRT – Stereotactic body radiation therapy
- SCA – Sickle cell anemia
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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.