LTOT

Medical abbreviation · Respiratory

LTOT
Stands forLong-term oxygen therapy
CategoriesMedical

LTOT stands for Long-term oxygen therapy, a respiratory abbreviation.

Home oxygen used for at least 15 hours a day, and ideally continuously, in patients with chronic lung disease and severe resting hypoxemia. It is the only COPD therapy besides smoking cessation shown to improve survival in that group.

Example: Resting PaO2 53 mmHg on two occasions: LTOT at 2 L/min for at least 15 hours daily.

Usage notes

Survival benefit was shown in the NOTT (1980) and British MRC (1981) trials for patients with a resting PaO2 of 55 mmHg or less (SpO2 88 percent or less). The LOTT trial (2016) found no benefit for moderate resting or exercise-induced desaturation. Smoking while using oxygen causes serious facial burns and house fires, so patients are counseled carefully.

More respiratory abbreviations

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  • LABA – Long-acting beta2-agonist
  • LAMA – Long-acting muscarinic antagonist
  • LLL – Left lower lobe
  • LPM – Liters per minute
  • LRTI – Lower respiratory tract infection
  • LUL – Left upper lobe
  • MART – Maintenance and reliever therapy
  • MV – Mechanical ventilation
  • NC – Nasal cannula
  • NIPPV – Noninvasive positive pressure ventilation
  • NIV – Noninvasive ventilation

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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.