CHOP

Medical abbreviation · Hematology and Oncology

CHOP
Stands forCyclophosphamide, hydroxydaunorubicin (doxorubicin), Oncovin (vincristine), prednisone
CategoriesMedical

CHOP stands for Cyclophosphamide, hydroxydaunorubicin (doxorubicin), Oncovin (vincristine), prednisone, a hematology and oncology abbreviation.

Combination chemotherapy regimen for non-Hodgkin lymphoma developed in the 1970s, still used for T-cell lymphomas and as the backbone of R-CHOP for B-cell lymphomas. It is typically given every three weeks.

Example: Peripheral T-cell lymphoma: CHOP plus etoposide (CHOEP) every 21 days.

Usage notes

A landmark 1993 trial showed that CHOP was as effective as more complex, more toxic regimens, cementing its place as the standard. The acronym mixes generic and brand names: H for hydroxydaunorubicin (doxorubicin) and O for Oncovin, the brand name of vincristine. Brentuximab vedotin is combined with a modified version (CHP) for CD30-positive T-cell lymphomas.

More hematology and oncology abbreviations

  • CA-125 – Cancer antigen 125
  • CAPOX – Capecitabine and oxaliplatin
  • CAR-T – Chimeric antigen receptor T-cell therapy
  • CAT – Cancer-associated thrombosis
  • CEA – Carcinoembryonic antigen
  • chemo – Chemotherapy
  • CLL – Chronic lymphocytic leukemia
  • CML – Chronic myeloid leukemia
  • CR – Complete response
  • CRAB – Hypercalcemia, renal insufficiency, anemia, bone lesions
  • CRS – Cytokine release syndrome
  • Cryo – Cryoprecipitate

See all 144 hematology and oncology abbreviations →

Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.