ASC-US

Medical abbreviation · Obstetrics & Gynecology

ASC-US
Stands forAtypical squamous cells of undetermined significance
CategoriesMedical

ASC-US stands for Atypical squamous cells of undetermined significance, an obstetrics & gynecology abbreviation.

The most common abnormal Pap result, meaning some cervical cells look slightly abnormal but not clearly precancerous. Management depends on HPV testing: a negative HPV result is reassuring, while a positive one usually leads to colposcopy.

Example: Pap ASC-US, reflex HPV positive (type 16); colposcopy scheduled.

Usage notes

The category comes from the Bethesda System for reporting cervical cytology, first published in 1988. Since 2019, ASCCP risk-based guidelines decide management from a patient's current result plus history. A related category, ASC-H, means a high-grade lesion cannot be excluded and always warrants colposcopy.

More obstetrics & gynecology abbreviations

  • AFI – Amniotic fluid index
  • AGA – Appropriate for gestational age
  • AMA – Advanced maternal age
  • AMH – Anti-Müllerian hormone
  • AROM – Artificial rupture of membranes
  • ART – Assisted reproductive technology
  • AUB – Abnormal uterine bleeding
  • BCP – Birth control pill
  • BPD – Biparietal diameter
  • BPP – Biophysical profile
  • BSO – Bilateral salpingo-oophorectomy
  • BTL – Bilateral tubal ligation

See all 89 obstetrics & gynecology abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.