ABVD
Medical abbreviation · Hematology and Oncology
| Stands for | Adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine |
|---|---|
| Categories | Medical |
ABVD stands for Adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine, a hematology and oncology abbreviation.
Standard chemotherapy for Hodgkin lymphoma, given intravenously on days 1 and 15 of each 28-day cycle. Early-stage disease typically needs two to four cycles, often with radiation, and advanced disease six cycles.
Example: Stage IIA Hodgkin: ABVD x2, interim PET Deauville 2, then AVD x2.
Usage notes
Developed by Gianni Bonadonna's group in Milan in the 1970s, it replaced the older MOPP regimen because it caused less infertility and fewer secondary leukemias. Bleomycin can cause serious lung toxicity, so it is often dropped after a negative interim PET scan, as supported by the RATHL trial (2016). Newer combinations replace bleomycin with brentuximab vedotin or nivolumab.
Related abbreviations
More hematology and oncology abbreviations
- 7+3 – Seven days of cytarabine plus three days of an anthracycline
- AC-T – Adriamycin (doxorubicin) and cyclophosphamide followed by Taxol…
- ADAMTS13 – A disintegrin and metalloproteinase with thrombospondin type 1…
- ADC – Antibody-drug conjugate
- AFP – Alpha-fetoprotein
- AIHA – Autoimmune hemolytic anemia
- AJCC – American Joint Committee on Cancer
- ALK – Anaplastic lymphoma kinase
- ALL – Acute lymphoblastic leukemia
- AML – Acute myeloid leukemia
- APL – Acute promyelocytic leukemia
- ASCO – American Society of Clinical Oncology
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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.