SPIRIT
Medical abbreviation · Medical Research
| Stands for | Standard Protocol Items: Recommendations for Interventional Trials |
|---|---|
| Categories | Medical |
SPIRIT stands for Standard Protocol Items: Recommendations for Interventional Trials, a medical research abbreviation.
Guideline listing the items a clinical trial protocol should contain, such as objectives, eligibility, interventions, outcomes, sample size, randomization, data management and ethics. It is the protocol counterpart to the CONSORT reporting guideline.
Example: Protocol drafted using the SPIRIT checklist before IRB submission.
Usage notes
First published in 2013 and updated in 2025 alongside CONSORT. Complete protocols help ethics committees, funders and later readers check whether published results match what was planned. An extension, SPIRIT-PRO, covers patient-reported outcomes.
Related abbreviations
More medical research abbreviations
- RWE – Real-world evidence
- SD – Standard deviation
- SDV – Source data verification
- SEM – Standard error of the mean
- SIV – Site initiation visit
- SOC – Standard of care
- SR – Systematic review
- STROBE – Strengthening the Reporting of Observational Studies in Epidemiology
- SUSAR – Suspected unexpected serious adverse reaction
- TEAE – Treatment-emergent adverse event
- TMF – Trial master file
- USPSTF – US Preventive Services Task Force
See all 94 medical research abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.