BZRA

Medical abbreviation · Drug Class

BZRA
Stands forBenzodiazepine receptor agonist
CategoriesMedical

BZRA stands for Benzodiazepine receptor agonist, a drug class abbreviation.

Group of sleep drugs acting at the benzodiazepine site of the GABA-A receptor, including benzodiazepines and the "Z-drugs" zolpidem, zaleplon and eszopiclone. In insomnia literature, BZRA usually refers mainly to the Z-drugs.

Example: Taper BZRA (zolpidem 10 mg) over 8 weeks with CBT-I support.

Usage notes

In 2019 the FDA added a boxed warning to the Z-drugs after reports of serious injuries and deaths from complex sleep behaviors such as sleepwalking and sleep-driving. Cognitive behavioral therapy for insomnia is recommended before BZRAs. Older adults face higher risks of falls and confusion, so the Beers Criteria advise avoidance.

More drug class abbreviations

  • BAS – Bile acid sequestrant
  • BB – Beta-blocker
  • BiTE – Bispecific T-cell engager
  • BL/BLI – Beta-lactam/beta-lactamase inhibitor
  • BTKi – Bruton tyrosine kinase inhibitor
  • BZD – Benzodiazepine
  • CAI – Carbonic anhydrase inhibitor
  • CCB – Calcium channel blocker
  • CDK4/6i – Cyclin-dependent kinase 4/6 inhibitor
  • CNI – Calcineurin inhibitor
  • COC – Combined oral contraceptive
  • COX-2 – Cyclooxygenase-2 selective inhibitor

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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.