BPaL

Medical abbreviation · Drug

BPaL
Stands forBedaquiline, pretomanid and linezolid
CategoriesMedical

BPaL stands for Bedaquiline, pretomanid and linezolid, a drug abbreviation.

Six-month all-oral regimen for highly drug-resistant tuberculosis, replacing older treatments that lasted up to two years and required daily injections. Adding moxifloxacin creates BPaLM.

Example: XDR-TB: start BPaL x 26 weeks; monitor CBC and vision on linezolid.

Usage notes

The regimen was based on the Nix-TB trial, which led to FDA approval of pretomanid in 2019, and the WHO recommended BPaLM for most multidrug-resistant TB in 2022. Linezolid toxicity, including nerve damage and low blood counts, is the main problem, and later trials found lower doses effective.

More drug abbreviations

  • AZT – Azidothymidine (zidovudine)
  • B12 – Vitamin B12 (cyanocobalamin)
  • BAL – British anti-Lewisite (dimercaprol)
  • BDQ – Bedaquiline
  • BIC – Bictegravir
  • bicarb – Sodium bicarbonate
  • BPO – Benzoyl peroxide
  • BSS – Balanced salt solution
  • CAB – Cabotegravir
  • CaCl – Calcium chloride
  • CaCO3 – Calcium carbonate
  • CBD – Cannabidiol

See all 170 drug abbreviations →

Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.