5-HTP

Medical abbreviation · Drug

5-HTP
Stands for5-Hydroxytryptophan
CategoriesMedical

5-HTP stands for 5-Hydroxytryptophan, a drug abbreviation.

Amino acid that the body converts directly into serotonin, sold as a supplement extracted from the seeds of the African plant Griffonia simplicifolia for mood, sleep and appetite control.

Example: Holding 5-HTP while patient starts escitalopram due to serotonin syndrome risk.

Usage notes

Taking 5-HTP with SSRIs, MAO inhibitors, triptans or tramadol can raise serotonin dangerously. Evidence for depression is limited to small, older studies. It differs from L-tryptophan, its precursor, whose contaminated supplements caused the 1989 eosinophilia-myalgia syndrome outbreak in the US.

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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.