3TC

Medical abbreviation · Drug

3TC stands for Lamivudine, a drug abbreviation.

Nucleoside reverse transcriptase inhibitor used in many HIV regimens, including the two-drug combination dolutegravir/lamivudine (Dovato), and at lower doses for hepatitis B.

Example: Simplified to DTG/3TC (Dovato) one tablet daily; viral load undetectable.

Usage notes

The name 3TC comes from its chemical description as a 3'-thiacytidine. It is well tolerated and inexpensive, making it a backbone of WHO-recommended regimens worldwide. A single mutation (M184V) causes high-level resistance, which paradoxically makes HIV less fit.

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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.